Ingano ya Aerosol Ingano: Igipimo Cyibanze Cyemeza Imikorere ya Nebulizer Clinical Imikorere no Kurushanwa Kumurongo

Kubakwirakwiza, abafite ibirango, hamwe nabikorera-label bakora bategura a compressor nebulizer  programme, impapuro zisobanura zikunda kugaragara - kugeza igishusho kimwe kigenzuwe: ingano ya aerosol. Ibice bibiri birashobora kwiruka byizewe, bikabyara igihu kigaragara, kandi bigatsinda ikizamini cyose, nyamara bigatanga ibyinshi mubipimo kumunwa no mumuhogo aho kugeza kuri bronchi cyangwa alveoli intego zandikiwe. Icyo cyuho kigaragaza nkibisubizo byumuyoboro udakomeye, igipimo cyo hejuru cyo kurega, nigiciro kidahamye.

Kubaguzi, ingano ya aerosol ntabwo ari ibisobanuro. Nibisobanuro bigomba gusomwa, kugereranywa, no kugenzurwa mbere yuko gahunda ya OEM / ODM ikorwa.

Impamvu Ingano ya Particle Ihitamo Niba Nebulizer ikora

Imiterere y ibihaha ishami ryayo ikora nka filteri ya aerodinamike isanzwe: uko intego igeze, niko ibice bigomba kuba bito.

• ibice binini birenze 5 µm kubitsa muri oropharynx no mumihanda yo hejuru, aho bamira aho kuyishiramo;

• ibice bya 2-5 µm bikwiranye nu mwuka wo hasi na bronchi - agace kagenewe asima na COPD;

• ibice bya 1-2 µm bigera mukarere ka alveolar;

• ibice biri munsi ya 0.5-1 µm bisohoka cyane mbere yo kubitsa.

Niyo mpamvu ibipimo ngenderwaho bifata ingano yingirakamaro nkibikorwa byibanze biranga. Munsi ya ISO 27427 (Umugereka C kubisohoka, Umugereka D wo gukwirakwiza ingano yingingo), ababikora bategerejweho kwerekana igabanywa - mubisanzwe nka MMAD nigice gihumeka - hamwe nigipimo cyibisohoka nubunini busigaye.

Imibare ine Inyuma Yibisobanuro

MMAD: Diameter ya Mass Median Aerodynamic

MMAD ni diameter ya aerodynamic aho 50% ya misa ya aerosol iba iri mubitonyanga byubunini cyangwa bito. Ikirere - ntabwo ari geometrike - diameter ni igipimo gikwiye, kuko kibara ubunini n'ubucucike. Kubuvura bwo mu kirere bwo hasi, MMAD mu gice cya 1-5 µm ni urwego rwingirakamaro mubuvuzi, hamwe na 2-4 µm bikunze kuvugwa kuri sisitemu ikora neza.

Igice gishimishije

MMAD yonyine irashobora kuyobya: isaranganya irashobora kwicara kuri 3 µm mugihe ushyira igice kinini cyayo hejuru ya 5 µm. Igice cyo guhumeka - ijanisha ryumubare wa aerosol munsi ya 5 µm - biziba icyuho. Ivuga umubare munini wimiti isohoka iri murwego rushobora kugera mumyuka yo hepfo.

GSD: Gutandukana kwa Geometriki

GSD isobanura uburyo gukwirakwiza gukwirakwiza hafi ya median. Ikizamini cya ISO 27427 gikunze gutanga raporo MMAD hamwe na GSD, kandi ibisobanuro bikunze kwibasira GSD ≤ 2.0.

Umubare usigaye

Ingano isigaye ni amazi asigaye mugikombe cyimiti iyo nebulisation ihagaze. Ntabwo ihindura ingano yubunini, ariko ihindura ingano yimiti yagenwe ihinduka aerosol. Umubare munini usigaye ugabanya bucece ibipimo byatanzwe kandi byongerera igihe cyo kuvura - byunvikana nabarwayi nka 'imashini ntirangiza ' hamwe numuyoboro nkibikoresho hamwe nibibazo.

Aho Dose Ijya

Gusoma bifatika biroroshye: akazi ka nebulizer ntabwo ari ugukora ibicu, ahubwo ni ugushira misa mumatsinda ya 1-5 µm. Ibindi byose bisohoka dose itigera igera kuntego.

Niki kigena Ingano ya Particle muri Compressor Nebulizer

• Jet na venturi geometrie - leveri yambere kubunini bwa median.

• Igishushanyo cya Baffle - ihindura spray yoroheje mugukwirakwiza guhumeka.

• Compressor airflow hamwe nigitutu - igipimo cyibisohoka nubunini buke bigenda hamwe, bityo pompe nigikombe bigomba kwemezwa nkibintu bihuye.

• Igishushanyo cy'igikombe no kuzuza amajwi - ISO 27427 imibare ihujwe nubunini bwuzuye bwuzuye hamwe numwirondoro uhumeka.

• Guhindura ibiyobyabwenge - guhagarikwa bitwara ibice bitarakemuka ubunini bwabyo bushobora kuganza ikwirakwizwa.

• Uburyo bukoreshwa - guhora hamwe no guhumeka-bikoresha ibishushanyo bitanga dosiye zitandukanye zingirakamaro uhereye kumurongo umwe.

Abatanga ibintu bibiri barashobora gusaba 'MMAD ≤ 5 µm ' kandi bagatanga ibice bitandukanye byubuhumekero mubice bitandukanye byuzuyemo ibiyobyabwenge bitandukanye. Ibisobanuro bihinduka gusa mugihe ibizamini byavuzwe kuruhande rwumubare.

Ingano yingirakamaro nkibisobanuro byubucuruzi

Uburyo Joytech ashyigikira abaguzi kumikorere ya Aerosol

Ubuvuzi bwa Joytech  bukora ibikoresho byubuzima bwo murugo kugirango bikwirakwizwe kwisi yose uhereye kuri compressor yibanze yibanze yoherejwe mubihugu birenga 150. Compressor nebulizer urwego - ikubiyemo abakuze, abana, abana, hamwe ninsanganyamatsiko SKUs murwego rwa NB - yicaye imbere muri gahunda ya OEM / ODM ishyigikira ibirango, gupakira, hamwe nibikoresho byabashinzwe gukwirakwiza ibicuruzwa.

Ku baguzi bakeneye imikorere ya aerosol kugirango babe mubucuruzi, Joytech atanga:

l  Iterambere rya Compressor nebulizer munsi ya ISO 13485 hamwe nigenzura ryakozwe, ukoresheje ibice byo mubuvuzi nibikoresho bya BPA.

l  Ubushobozi bwo kwipimisha imbere burimo gukwirakwiza ingano, hamwe na EMC, umutekano w'amashanyarazi, hamwe no gusuzuma imikoreshereze

Kwemeza  pompe compressor hamwe nigikombe cyimiti nka sisitemu ihuye, bityo igipimo gisohoka nogukwirakwiza ibice byatejwe imbere aho kwigenga

l  Impamyabumenyi zirimo CE MDR (EU 2017/745), Uruhushya rwibikoresho byubuvuzi muri Kanada, hamwe na MHRA, hamwe na moderi zatoranijwe zitwara FDA 510 (k)

l  100+ Inzobere za R&D zishyigikira guhuza inyandiko hamwe namabwiriza agenga amabwiriza

Ibidukikije  byangiza ibidukikije ibikoresho bya nebulizer  - ibikombe by'imiti, abakuze / umwana / masike y'impinja, umunwa, hamwe no guhumeka ikirere

l  Umusaruro muri 260.000+ sqm yo gukora ibirenge, ushyigikiwe na 100+ patenti

Icyerekezo cy'isoko: Igicu ntabwo aricyo gisobanura

Mugihe ubuvuzi bwubuhumekero bugenda bugana ibyangombwa byinshi, byateganijwe neza, hamwe nubuhanga bwumuyoboro wabigize umwuga, ibicuruzwa bifite umwanya wabyo nibyo bizaba imikorere ya aerosol ishobora kuvugwa aho kugaragazwa nuburyo bugaragara. Ingano ya Aerosol ni igisobanuro gishobora kugenzurwa, kugereranywa, no kubakwa mu bicuruzwa bidashobora kwirwanaho - ariko gusa hamwe nuwabikoze abipima, akabyandika, kandi ashobora gusubiramo ibisubizo ku gipimo cy’umusaruro.

Umufatanyabikorwa natwe

Kugirango uganire kuri nebulizer OEM / ODM gahunda, saba ibyiciro ibyangombwa, cyangwa utegure ingero zo gusuzuma tekiniki, hamagara sale14@sejoy.com.

Ibibazo

Q1: Niki MMAD nziza kuri nebulizer?

Ku buvuzi bwo mu kirere buke nka asima na COPD, MMAD mu ntera ya 1-5 µm isanzwe ifatwa nkitsinda rifite akamaro kivura, hamwe na 2-4 µm bikunze kuvugwa kuri sisitemu ikora neza. Hindura MMAD hamwe nigice gihumeka hamwe na GSD - umuhuza wenyine ntagaragaza ingano yimiti ifite akamaro.

Q2: Kuki igice cyubuhumekero gifite agaciro kuruta MMAD yonyine?

MMAD ivuga aho hagati yo kugabana yicaye, ntabwo ingano yingirakamaro ari ingirakamaro. Igice gishimishije gitanga igipimo cya misa ya aerosol yasohotse munsi ya 5 µm - igice gishobora kugera mumihanda yo hepfo. Nebulizers ebyiri zifite imibare imwe ya MMAD zirashobora gutandukana cyane mubice byubuhumekero, kandi iryo tandukaniro risobanura ibipimo byatanzwe hamwe nubuvuzi.

Q3: Ingano yingirakamaro ihinduka hamwe nubunini bwuzuye cyangwa imiti?

Yego. Ikwirakwizwa nigisohoka gipimirwa kubijanye no kuzuza amajwi no guhumeka neza, kandi imikorere kubindi byuzuzanya ntabwo ihita ihwanye. Guhagarikwa bitwara ibice bitarakemuka ubunini bwabyo bigira ingaruka kubitandukanye bitandukanye nigisubizo. Gereranya abatanga gusa nubunini bwuzuye, ibiyobyabwenge bipimisha, nuburyo bwo gupima byavuzwe.